Bezafibrate is prescribed for the treatment of high blood cholesterol when dietary measures have proven ineffective. The medication lowers lipid (fat) levels in the blood and is particularly effective when the levels of HDL-cholesterol – often termed “good” cholesterol because it tends to carry cholesterol away from the arteries and back to the liver, where it’s passed from the body – is low, and triglycerides – a type of fat that is normally present in the blood, and of which high levels are linked to heart disease and atherosclerosis – are raised.
When bezafibrate is taken, blood cholesterol is reduced by as much as 15-20 percent, and the risk of coronary heart disease (angina and/or heart attacks) is reduced significantly.
How does bezafibrate work?
Bezafibrate appears to interfere with the conversion of fatty acids to different types of fat in the liver.
Drug schedule: Schedule 3
Available as: Tablets and modified-release tablets
What does it do? Lowers high blood cholesterol
Overdose risk: Low
Dependency risk: Low
Available as a generic? Yes
Available on prescription only? Yes
Onset of effect: It may take several weeks to show a noticeable effect
Duration of action: Up to 24 hours
Dietary advice: A low-fat diet need to be followed for bezafibrate to give optimal results. The tablets should be taken with meals.
Stopping: Use as directed by your doctor. Do not stop treatment without speaking to your prescriber
Prolonged use: No problem expected. However, if you have kidney or liver disease, you should be closely monitored if using for prolonged periods.
Alert your doctor before using this drug if:
- You have severe kidney or liver disease,
- You have an overactive thyroid gland,
- You have gallstones or gall bladder disorders,
- You have a stomach ulcer,
- You have heart disease, or
- You are taking other medication.
Pregnancy: Avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.
Breastfeeding: Avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: Avoid. This medication may cause serious adverse effects. Consult your doctor before use.
Infants and children: This medication is not intended for use in children. It has been used under medical supervision in children over the age of 4 without significant adverse effects.
Elderly: No special precautions need be taken.
Driving and hazardous work: No special precautions need be taken.
Alcohol: No special precautions need be taken.
Source Reference – Health24.com