Fluconazole is an antibiotic medication used for the treatment of fungal and yeast infections that affect the mouth, vagina, nails and skin and that did not respond to conventional topical treatment. It is furthermore indicated in the treatment of systemic fungal infections. It is of particular use in the treatment of cryptococcal meningitis – a fungal infection of the membranes lining the central nervous system – in patients with Aids.
This medication is only effective in treating fungal infections and will not be effective in treating bacterial or viral infections.
Fluconazole can also be used to prevent fungal infections in patients with defective immunity.
How does fluconazole work?
Fluconazole inhibits the manufacturing of substances vital for fungal growth and functioning.
Fast facts
Drug schedule: schedule 4
Available as: fluconazole is available as capsules, suspension and as injection
What does it do? fluconazole has an anti-fungal action
Overdose risk: medium
Dependence risk: low
Is fluconazole available as a generic? yes
Is fluconazole available on prescription only ? yes
User information
Onset of effect: the full effect of this medication may only be seen within a few days
Duration of action: up to 24 hours
Dietary advice: fluconazole can be taken with, or without food
Stopping this medicine : complete the full course as directed by your doctor; even if you feel better, symptoms may recur with premature discontinuation
Prolonged use: fluconazole is generally not used for prolonged periods of time; liver function tests may be periodically required
Special precautions
Consult your doctor before using this drug if:
- you have liver or kidney disease
- you are taking any other medication
Pregnancy: avoid. Potential risk to the foetus has been reported. Consult your doctor before use, or if you are planning to fall pregnant.
Breastfeeding: avoid. It is unknown how this medication may affect your baby. Consult your doctor before use.
Porphyria: avoid. This medication may cause serious adverse effects. Consult your doctor before use.
Infants and children: a reduced dose is needed when prescribed in infants and children.
The elderly: caution is advised in the elderly in case of impaired kidney function.
Driving and hazardous work: no special precautions need to be taken.
Alcohol: no special precautions need to be taken.
Source Reference – Health24.com
